Personal Nutrition uses an in-depth questionnaire covering nutrition, lifestyle, physical activity, prescription medications, sleep, food preferences and more. This information allows Persona to create vitamin packages with all the nutrients you need.

You can receive packages of vitamins with instructions to take them at specific times of the day because the bioavailability of any particular nutrient depends on what else is in your body at the time.

For example, it is best to take water-soluble vitamins like vitamin C or any B vitamin after waking up because an empty stomach will help you absorb them. Fat-soluble vitamins like vitamins K and E, on the other hand, are best taken with a meal because your body doesn’t absorb the vitamins without the help of dietary fat. Some vitamins should also be taken in tandem to ensure absorption (such as vitamin D and calcium).

Persona Nutrition ships orders every 28 days. Your vitamins come in convenient daily packets designed to be taken in the morning, afternoon and evening, depending on the content of your subscription. Persona offers nearly 100 products, and the cost of your box will vary based on which products you add to your subscription. The brand offers personalized vitamin packages for $30 a month.

HUM Nutrition Begins with a person’s personal struggle with skin eruptions and blemishes. Founder Walter Faulstroh found that prescription drugs only worked for him temporarily, and topical treatments left his skin — and his confidence — scarred.

HUM began making vitamin supplements intended to contribute to healthy, clear skin, but the brand has since expanded to include a comprehensive offering of products for hair and nails, digestion, immunity, energy, bones and joints, sleep, stress and metabolism.

A 3-minute quiz will unlock your wellness profile and a free consultation with a registered dietitian. Your HUM profile reveals what the company says is your most effective combination of nutrients, vitamins and minerals plus your RD’s advice. You can choose to stick with your recommendations or shop for other products.

You will receive your HUM subscription box every 30 days, whether you sign up for a month-to-month subscription or buy a plan for three, six or 12 months.

The price of your subscription box will vary based on which vitamins and nutrients you choose. Hum’s products range from $12 to $116. HUM ships worldwide and shipping is free for all orders over $50.

You are a vitamin founded by two doctors who continue to see patients who come in with similar symptoms — fatigue, lack of focus, thinning hair, skin problems and more — and continue to trace these issues back to nutrient deficiencies or bad eating habits.

You start with a questionnaire that asks all the basics, plus questions about how you sleep, eat and move. You will also provide information about any health conditions you have or medications you are taking.

I like Vous Vitamin because it’s just one pill. Instead of vitamin packets containing two to six pills, Vous Vitamin packs all of your recommended nutrients into one caplet that you take twice a day (you can take one pill in the morning and one in the evening, or take both at the same time).

You can also purchase individual “situational supplements,” such as Recovery Act (a hangover cure) and PROGRESS (an energy boost), just in case you need a little something extra.

Vous Vitamins are delivered every three months or every six months, and shipping is free. You can save more money every month if you choose the six-month subscription.

Thesis unique in that it focuses on addressing specific symptoms with supplements, rather than estimating nutrient needs based on a lifestyle quiz. You still take a quiz — and there’s an algorithm to determine the dosage of ingredients — but your recommendations are based on your answers to questions like, “How long is your average attention span?”

The main focus of the thesis is on brain health and cognitive function, rather than the whole body approach that other vitamin subscription services take. The thesis approach also narrows the supplement down to a specific category: nootropics.

Nootropics, according to Thesis, are “nutrient compounds that have been shown to improve mental performance in areas such as motivation, creativity, mood, memory, focus, and thought processing.”

Thesis packages are sent once a month, and shipping is free within the US. You can also choose a one-time purchase.

Rootine Boasting one of the most robust data collection methods of all vitamin subscription services. Like the others, it starts with a quiz about your lifestyle, and the company says it uses this information, in addition to your age and body size, to calculate your exact needs for micronutrients and minerals and a balanced diet.

To further customize, you can order a DNA test on your first purchase or input data you already have from a service like background or 23 and I.

If you have data from a blood test on hand, you can also upload that for a doctor’s review (or, you can order Rootine’s blood test). Rootine says you need your demographics (age, weight etc.), lifestyle, DNA information and blood analysis to create your personalized vitamin package.

Rootine then gives you a detailed profile of all its recommended vitamins, explaining what they do and why the company believes you need them. Free shipping on orders over $45.

Supplement subscriptions can be a great way to meet your daily needs if you lack certain vitamins. Talking to your doctor to find out what nutritional deficiencies you need to fill is important before you invest in any vitamin subscriptions. Many people get all of them nutritional needs from their diet, so checking with your doctor is the best way to make sure you’re not wasting your money on supplements you don’t need.

If you’re vitamin deficient, it’s worth investing in vitamins and supplements to make sure your body has what it needs. However, a higher price is not always an indication of higher quality. It’s best to look at the nutrition label to check if the ingredient list and nutrient levels match your needs.

It all depends on the quality and your needs. Brands that use high quality ingredients with third party testing and clear label usually safe. We also recommend reading online reviews from existing customers and consulting with a healthcare professional to make the right choice.

The cost of a vitamin subscription depends on how many vitamins you buy, the type, and your unique health profile. With that in mind, we estimate the cost of a monthly subscription to be in the range of $30 to $300.